GLOBE AND MAIL - November 27, 2010 |
By Caroline Alphonso and Siri Agrell |

It has been a year since Paolo Zamboni offered the hope of liberation to multiple sclerosis patients everywhere.
The Italian doctor suggested that some cases are vascular disorders caused by vein blockages that lead to a build-up of iron in the brain. The possible way to free up the compromised blood flow – called chronic cerebro-spinal venous insufficiency (CCSVI) – is angioplasty. The procedure uses tiny balloons to open constricted veins.

Since then, hundreds of Canadians have sought out the unproven treatment overseas, paying tens of thousands of dollars out of pocket to have their veins opened up with balloons and stents. One of them, an Ontario resident named Mahir Mostic, died last month from complications after undergoing the procedure at a Costa Rican clinic.

As Canadians look abroad for relief, Ottawa has advised that clinical trials be delayed until more evidence is gathered about the connection between blocked veins and MS. This week, as Newfoundland announced that it would observe a group of patients seeking treatment outside the country, Caroline Alphonso and Siri Agrell set out to do the same.

Steve Garvie, 53, Barrie, Ont.

Diagnosed in 2000 with secondary progressive MS.

Treated in January at the Royal Victoria Hospital in Barrie.

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