OTTAWA - The Honourable Leona Aglukkaq, Minister of Health, today accepted the recommendations on Multiple Sclerosis (MS) research recently presented to her by Canadian Institutes of Health Research (CIHR) President Dr. Alain Beaudet. These recommendations are based on a thorough review of the current state of science conducted at an August 26, 2010, meeting of leading North American MS experts.

"At the meeting organized by CIHR and the MS Society of Canada, the scientific experts agreed that there is an overwhelming lack of scientific evidence that there is any link between abnormal venous drainage and MS," said Dr. Alain Beaudet, CIHR President.

"I accept the expert group's recommendation that we await the outcome of studies currently underway that are exploring the relationship between MS and venous malformations," said Minister Aglukkaq. "These studies will inform decisions about moving forward with any pan-Canadian clinical trials on a treatment to unblock veins. I will immediately establish a scientific expert working group to monitor and keep me informed of progress on these and other studies. More details on this working group will be available in the near future."

The scientific experts unanimously agreed that it was premature to support a pan-Canadian trial on the treatment of abnormal venous drainage, also known as the "Liberation Procedure" initiated by Dr. Zamboni of Italy.

The Government of Canada will accept the following three recommendations:

1.To establish a scientific expert working group made up of the principal investigators for the seven MS Society-sponsored studies (four from Canada and three from the US), scientific leadership from CIHR and the MS Societies, and a representative from the provinces and territories, to monitor and analyze preliminary and final results from these studies, as well as from related studies from around the world. The first meeting of this expert working group should take place in this calendar year.
2.Based on the outcomes of these studies, the scientific expert working group should reach conclusions regarding (1) the association (or lack thereof) between impaired cerebral venous drainage and MS; and (2) a common standard for reliably diagnosing the condition using imaging or other techniques.
3.Depending on these conclusions, the scientific expert working group should make recommendations on further studies including, if appropriate, a pan-Canadian interventional clinical trial.