October 19, 2011 - A new meta analysis concludes there is a strong and statistically significant association between chronic cerebrospinal venous insufficiency (CCSVI) and multiple sclerosis (MS), although it raises questions about the blinding of the included studies and the protocol used by technicians evaluating ultrasound results. However, marked heterogeneity among the studies prevents a definitive conclusion about the role of CCSVI in MS, the researchers add. "If you're one of those who believes that CCVSI causes MS, I don't think this study tells us that, but conversely, if you're one of the skeptics who says that it's all a bunch of nonsense, this study suggests that maybe that's not the case," lead author Andreas Laupacis, MD,
a general internist and executive director, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada, said to Medscape Medical News. The study was published online October 3 in the Canadian Medical Association Journal.

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